Question: How Do You Read CSF Results?

What is the normal range for CSF opening pressure?

What is a Normal Opening Pressure.

The normal range for CSF is reported differently in various sources, with most reporting a normal range of 7-18 cmH2O in adults,1 though some consider the normal range 5-25 cmH2O.

However, a pressure >25 cmH2O or <5 cmH2O should certainly prompt you to look for a source..

What is considered high protein in CSF?

EVALUATION. Spinal fluid protein concentration is usually moderately elevated, with concentrations in the 150 to 300 mg/100 mL range.

What does CSF fluid look like?

Clear, watery drainage usually from only one side of the nose or one ear when tilting the head forward. Salty or metallic taste in mouth. Drainage down back of throat. Loss of smell.

What is the normal range of CSF protein?

The normal protein range varies from lab to lab, but is typically about 15 to 60 milligrams per deciliter (mg/dL) or 0.15 to 0.6 milligrams per milliliter (mg/mL). Normal value ranges may vary slightly among different laboratories. Talk to your health care provider about the meaning of your specific test results.

Why is protein high in CSF?

An abnormal protein level in the CSF suggests a problem in the central nervous system. Increased protein level may be a sign of a tumor, bleeding, nerve inflammation, or injury. A blockage in the flow of spinal fluid can cause the rapid buildup of protein in the lower spinal area.

How do you assess CSF?

A CT cisternogram involves using a contrast injected into the spinal fluid through a spinal tap and then performing CT scans. This test identifies the exact location of the CSF leak and the pathway of the drainage into the nose.

What can CSF tell you?

A CSF analysis may include tests to diagnose: Infectious diseases of the brain and spinal cord, including meningitis and encephalitis. CSF tests for infections look at white blood cells, bacteria, and other substances in the cerebrospinal fluid.

How do you get rid of CSF?

A lumbar puncture (spinal tap) is performed in your lower back, in the lumbar region. During a lumbar puncture, a needle is inserted between two lumbar bones (vertebrae) to remove a sample of cerebrospinal fluid. This is the fluid that surrounds your brain and spinal cord to protect them from injury.

What does blood in CSF indicate?

Finding red blood cells in the CSF may be a sign of bleeding. However, red blood cells in the CSF may also be due to the spinal tap needle hitting a blood vessel. Additional conditions which this test may help diagnose include: Arteriovenous malformation (cerebral) Cerebral aneurysm.

What is the normal percentage of lymphocytes in CSF?

Normal WBC count in CSF is < 5 cells/µl. In differential count, mononuclear cells should predominate (60-70% of it being small lymphocytes and 30-40% monocytes) and only occasional mature neutrophils are found (< 1%, excluding blood contamination). Elevation of nucleated cells in the CSF is called pleocytosis.

What are normal CSF values?

Normal Results CSF total protein: 15 to 60 mg/100 mL. Gamma globulin: 3% to 12% of the total protein. CSF glucose: 50 to 80 mg/100 mL (or greater than two thirds of blood sugar level) CSF cell count: 0 to 5 white blood cells (all mononuclear), and no red blood cells.

What is a normal lumbar puncture result?

Normal lumbar puncture (LP) cerebrospinal fluid (CSF) findings include the following: Appearance: Clear. Opening pressure: 10-20 cm H2 O. WBC count: 0-5 cells/µL (< 2 polymorphonucleocytes [PMN]); normal cell counts do not rule out meningitis or any other pathology.

What is normal CSF pressure in adults?

Normal CSF contains 0-5 mononuclear cells. The CSF pressure, measured at lumbar puncture (LP), is 100-180 mm of H2O (8-15 mm Hg) with the patient lying on the side and 200-300 mm with the patient sitting up.

Does high protein in CSF mean MS?

Cerebral Spinal Fluid Studies Oligoclonal Immunoglobulin Bands can be identified in the CSF of MS patients via electrophoresis. The overall protein level is also slightly elevated – up to 0.1 g/L. Protein level can be higher if the patient is going through a marked relapse (i.e.,. severe optic neuritis).

Is a CSF leak an emergency?

A CSF leak is a serious health issue. It involves this type of fluid escaping through a tear in the dura mater. The symptoms of a CSF leak include fluid drainage from the ears or nose and a headache that worsens when the head is upright.